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Although there are no studies that have specifically examined the effects of CGRP on muc5AC or muc5B expression in COPD, finding altered CGRP receptor expression in COPD airway epithelial cells suggests a possible influence of CGRP on muc5AC and muc5B expression

However, for patients with severe symptomatic hyponatremia who are particularly prone to overcorrectionespecially those at high risk for ODS where consistent monitoring of laboratory values and urine output is challengingearly use of DDAVP can be considered a proactive and viable strategy

Disclaimer: This information reflects findings from preclinical and observational research

Mol Pharm 13:34683477